Arcaine sulfate salt
SIGMA/A0384
Synonym: 1,4-
CAS Number: 14923-17-2
Empirical Formula (Hill Notation): C6H16N6 · H2O4S
Molecular Weight: 270.31
MDL Number: MFCD00050545
Linear Formula: C6H16N6 · H2O4S
Product Type: Chemical
| assay | ≥98% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C6H16N6.H2O4S/c7-5(8)1 |
| InChI key | RWTGFMPOODRXIM-UHFFFAOYSA |
| mp | >280 °C |
| Quality Level | 200 ![]() |
| SMILES string | OS(O)(=O)=O.NC(=N)NCCCCNC |
| solubility | 1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| Application: | Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist: • to evaluate its effects on the acquisition of electrical kindling of the amygdala • to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage • to study its effects on cell-free translation of synthetic polynucleotide |
| Biochem/physiol Actions: | Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders. |
| Packaging: | 50 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | >280 °C |
| UNSPSC | 12352200 |

