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Arcaine sulfate salt

SIGMA/A0384

Synonym: 1,4-Diguanidinobutane sulfate salt

CAS Number: 14923-17-2
Empirical Formula (Hill Notation): C6H16N6 · H2O4S
Molecular Weight: 270.31
MDL Number: MFCD00050545
Linear Formula: C6H16N6 · H2O4S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-A0384-50MG 50 mg
$139.00
1/EA
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assay ≥98% (TLC)
biological source synthetic (organic)
form powder
InChI 1S/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)
InChI key RWTGFMPOODRXIM-UHFFFAOYSA-N
mp >280 °C
Quality Level 200 
SMILES string OS(O)(=O)=O.NC(=N)NCCCCNC(N)=N
solubility 1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
Application: Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist:
• to evaluate its effects on the acquisition of electrical kindling of the amygdala
• to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage
• to study its effects on cell-free translation of synthetic polynucleotide

Biochem/physiol Actions: Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders.
Packaging: 50 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp >280 °C
UNSPSC 12352200

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