Aurothioglucose hydrate

SIGMA/A0606 - ≥96% (titration)

Synonym: Gold thioglucose; Solganal; Solganol

CAS Number: 12192-57-3 (anhydrous)
Empirical Formula (Hill Notation): C₆H₁₁AuO₅S · xH₂O
Molecular Weight: 392.18 (anhydrous basis)
EC Number: 235-365-7
Linear Formula: C₆H₁₁AuO₅S · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A0606-5MG	5 mg	$201.00 1/EA	Add To Favorites
45-A0606-25MG	25 mg	$693.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥96% (titration)
color	white to beige
form	powder
InChI	1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
InChI key	SGVIEHTYEMEDRR-PKXGBZFFSA-M
Quality Level	100
SMILES string	O.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
solubility	H₂O: 5 mg/mL, clear
storage condition	desiccated
storage temp.	2-8°C

Application:	Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.
Biochem/physiol Actions:	Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC₅₀ approximately 1 μM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer.
Features and Benefits:	This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P280 - P342 + P311
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	22-36/37-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥96% (titration)
Storage Temp.	2-8°C
UNSPSC	12352200

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