DL-2-Aminoadipic acid
SIGMA/A0637 - ≥99%
Synonym: DL-α-Aminoadipic acid
CAS Number: 542-32-5
Empirical Formula (Hill Notation): C6H11NO4
Molecular Weight: 161.16
EC Number: 208-809-2
MDL Number: MFCD00063119
Linear Formula: HO2C(CH2)3CH(NH2)CO2H
Product Type: Chemical
assay | ≥99% |
form | powder |
InChI | 1S/C6H11NO4/c7-4(6(10)11) |
InChI key | OYIFNHCXNCRBQI-UHFFFAOYSA |
mp | 196-198 °C (lit.) |
Quality Level | 200 |
SMILES string | NC(CCCC(O)=O)C(O)=O |
storage temp. | 2-8°C |
Application: | DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity. |
Biochem/physiol Actions: | DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity. |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H317 |
Precautionary statements | P280 |
Hazard Codes | Xi |
Risk Statements | 43 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% |
mp | 196-198 °C (lit.) |
Storage Temp. | 2-8°C |
UNSPSC | 12352106 |