DL-2-Aminoadipic acid
SIGMA/A0637 - ≥99%
Synonym: DL-α-Aminoadipic acid
CAS Number: 542-32-5
Empirical Formula (Hill Notation): C6H11NO4
Molecular Weight: 161.16
EC Number: 208-809-2
MDL Number: MFCD00063119
Linear Formula: HO2C(CH2)3CH(NH2)CO2H
Product Type: Chemical
| assay | ≥99% |
| form | powder |
| InChI | 1S/C6H11NO4/c7-4(6(10)11) |
| InChI key | OYIFNHCXNCRBQI-UHFFFAOYSA |
| mp | 196-198 °C (lit.) |
| Quality Level | 200  |
| SMILES string | NC(CCCC(O)=O)C(O)=O |
| storage temp. | 2-8°C |
| Application: | DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity. |
| Biochem/physiol Actions: | DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280 |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 196-198 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352106 |