L-Azetidine-2-carboxylic acid
SIGMA/A0760 - ≥99%
Synonym: (S)
CAS Number: 2133-34-8
Empirical Formula (Hill Notation): C4H7NO2
Molecular Weight: 101.10
EC Number: 218-362-5
MDL Number: MFCD00005166
Linear Formula: C4H7NO2
Product Type: Chemical
assay | ≥99% |
form | powder |
InChI | 1S/C4H7NO2/c6-4(7)3-1-2-5 |
InChI key | IADUEWIQBXOCDZ-VKHMYHEASA |
Quality Level | 200 |
SMILES string | OC(=O)[C@@H]1CCN1 |
Application: | • collagen synthesis inhibitor • protein folding antagonist • as a standard in liquid chromatography-mass spectrometry |
Biochem/physiol Actions: | Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding. |
Biochem/physiol Actions: | L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic. It is a four-membered ring analog of L-proline that causes protein misconstruction when incorporated instead of proline. |
General description: | |
Packaging: | 1 g in poly bottle |
Packaging: | 50, 100, 250 mg in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% |
UNSPSC | 12352209 |