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3-Aminobenzamide

SIGMA/A0788 - ≥99% (TLC)

Synonym: 3-AB; 3-ABA

CAS Number: 3544-24-9
Empirical Formula (Hill Notation): C7H8N2O
Molecular Weight: 136.15
EC Number: 222-586-9
MDL Number: MFCD00007989
Linear Formula: H2NC6H4CONH2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A0788-100MG 100 mg
 $87.50
1/EA		 Add To Favorites
45-A0788-250MG 250 mg
 $144.00
1/EA		 Add To Favorites
45-A0788-1G 1 g
 $432.00
1/EA		 Add To Favorites
45-A0788-5G 5 g
 $1800.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0788-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0788-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0788-250MG

 

assay ≥99% (TLC)
color white to off-white
form powder
InChI 1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
InChI key GSCPDZHWVNUUFI-UHFFFAOYSA-N
mp 115-116 °C (lit.)
SMILES string NC(=O)c1cccc(N)c1
solubility DMSO: soluble
  ethanol: 50 mg/mL, clear, light yellow
  H2O: soluble (may require gentle heating)
storage temp. room temp
Application: 3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.
Biochem/physiol Actions: 3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.
Features and Benefits: This compound is a featured product for Apoptosis research. Click here  to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 1, 5 g in poly bottle
Packaging: 100, 250 mg in poly bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥99% (TLC)
mp 115-116 °C (lit.)
Storage Temp. room temp
UNSPSC 12352200

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