N-Acetylneuraminic acid

SIGMA/A0812 - ≥95% anhydrous basis, synthetic

Synonym: 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid; Lactaminic acid; NAN; NANA; Sialic acid

CAS Number: 131-48-6
Empirical Formula (Hill Notation): C₁₁H₁₉NO₉
Molecular Weight: 309.27
EC Number: 205-023-1
MDL Number: MFCD00006620
Linear Formula: C₁₁H₁₉NO₉
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A0812-25MG	25 mg	$70.60 1/EA	Add To Favorites
45-A0812-100MG	100 mg	$193.00 1/EA	Add To Favorites
45-A0812-250MG	250 mg	$346.00 1/EA	Add To Favorites
45-A0812-1G	1 g	$948.00 1/EA	Add To Favorites

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This image depicts SKU: A0812-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% anhydrous basis
biological source	synthetic
color	white to off-white
form	powder
InChI	1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
InChI key	SQVRNKJHWKZAKO-PFQGKNLYSA-N
mp	184-186 °C
Quality Level	200
SMILES string	O[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O
solubility	H₂O: ~50 mg/mL
storage temp.	−20°C
type	Type IV-S

Application:	N-Acetylneuraminic acid (NANA, Neu5Ac) is a major component of glycoconjugates such as glycolipids, glycoproteins and proteoglycans (sialogylcoproteins) where it confers selective binding characteristics to the glycosylated component. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.
Biochem/physiol Actions:	Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.
Other Notes:	To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Packaging:	1 g in poly bottle
Packaging:	25, 100, 250 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P264 - P280 - P305 + P351 + P338 - P337 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2

Purity	≥95% anhydrous basis
mp	184-186 °C
Storage Temp.	−20°C
UNSPSC	12352201

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