N-Acetyl-Asp-Glu-Val-Asp-al

SIGMA/A0835 - ≥95%, powder

Synonym: Ac-DEVD-CHO

CAS Number: 169332-60-9
Empirical Formula (Hill Notation): C₂₀H₃₀N₄O₁₁
Molecular Weight: 502.47
MDL Number: MFCD00671412
Linear Formula: C₂₀H₃₀N₄O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A0835-1MG	1 mg	$178.00 1/EA		Add To Favorites
45-A0835-5MG	5 mg	$613.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
biological source	synthetic
color	white
form	powder
InChI	1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)
InChI key	UMBVAPCONCILTL-UHFFFAOYSA-N
Quality Level	100
SMILES string	[H]C(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C
solubility	H₂O: 1 mg/mL
storage temp.	−20°C

Amino Acid Sequence:	NAc-Asp-Glu-Val-Asp-al
Application:	N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
Biochem/physiol Actions:	N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
Biochem/physiol Actions:	Reversible inhibitor of IL-1β converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).
General description:	N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352209

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