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A-740003

SIGMA/A0862 - ≥98% (HPLC)

Synonym: N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide

CAS Number: 861393-28-4
Empirical Formula (Hill Notation): C26H30N6O3
Molecular Weight: 474.55
MDL Number: MFCD09970333
Linear Formula: C26H30N6O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A0862-5MG 5 mg
 $146.00
1/EA		 Add To Favorites
45-A0862-25MG 25 mg
 $584.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C26H30N6O3/c1-26(2,3)24(31-23(33)15-17-11-12-21(34-4)22(14-17)35-5)32-25(29-16-27)30-20-10-6-9-19-18(20)8-7-13-28-19/h6-14,24H,15H2,1-5H3,(H,31,33)(H2,29,30,32)
InChI key PUHSRMSFDASMAE-UHFFFAOYSA-N
Quality Level 100 
SMILES string COc1ccc(CC(=O)NC(NC(Nc2cccc3ncccc23)=NC#N)C(C)(C)C)cc1OC
solubility DMSO: 10 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: A-740003 is a selective P2X7 purinoceptor antagonist.
Features and Benefits: This compound is featured on the P2 Receptors: P2X Ion Channel Family  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: A-740003 is a highly affine and selective P2X7 receptor antagonist and is best for the progression of a radiotracer for imaging of neuroinflammation by positron emission tomography.
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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