Angelicin
SIGMA/A0956
Synonym: 2-
CAS Number: 523-50-2
Empirical Formula (Hill Notation): C11H6O3
Molecular Weight: 186.16
MDL Number: MFCD00064930
Linear Formula: C11H6O3
Product Type: Chemical
form | powder |
InChI | 1S/C11H6O3/c12-10-4-2-7-1 |
InChI key | XDROKJSWHURZGO-UHFFFAOYSA |
Quality Level | 200 |
SMILES string | O=C1Oc2c(C=C1)ccc3occc23 |
storage temp. | 2-8°C |
Application: | Angelicin, an angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis. |
Biochem/physiol Actions: | Angular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor cells. |
Packaging: | 10, 25 mg in poly bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H315 - H319 - H335 |
Precautionary statements | P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38-40 |
Safety Statements | 26-36/37/39 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 85151701 |