n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate

SIGMA/A0987 - ≥98% (HPLC)

Synonym: Cytosporone A n-amyl ester; compound 10i

CAS Number: 1257228-26-4
Empirical Formula (Hill Notation): C₂₂H₃₄O₅
Molecular Weight: 378.50
MDL Number: MFCD18632550
Linear Formula: C₂₂H₃₄O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A0987-5MG	5 mg	$125.00 1/EA		Add To Favorites
45-A0987-25MG	25 mg	$510.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white
form	powder
InChI	1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3
InChI key	FCKDHZVFIMRCNM-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCCCCC
solubility	DMSO: >65 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist.
Biochem/physiol Actions:	n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.
Features and Benefits:	This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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