N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin
SIGMA/A1086 - ≥97% (HPLC), powder
Synonym: Ac-DEVD-AMC
CAS Number: 169332-61-0
Empirical Formula (Hill Notation): C30H37N5O13
Molecular Weight: 675.64
MDL Number: MFCD00671411
Linear Formula: C30H37N5O13
Product Type: Chemical
assay | ≥97% (HPLC) |
color | white |
composition | Peptide content, ~65% |
form | powder |
InChI | 1S/C30H37N5O13/c1-13(2)26 |
InChI key | ALZSTTDFHZHSCA-RNVDEAKXSA |
Quality Level | 100 |
SMILES string | CC(C)[C@H](NC(=O)[C@H](CC |
solubility | DMSO: 10 mM |
storage temp. | −20°C |
Application: | N-Acetyl-Asp-Glu-Val-Asp-7 |
Biochem/physiol Actions: | Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. |
Features and Benefits: | This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Features and Benefits: | This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 5 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥97% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352209 |