DMT-dA(bz) Phosphoramidite

SIGMA/A111000

Synonym: DMT-dA(bz) Amidite; N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyadenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyadenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

CAS Number: 98796-53-3
Empirical Formula (Hill Notation): C₄₇H₅₂N₇O₇P
Molecular Weight: 857.93
MDL Number: MFCD00036314
Linear Formula: C₄₇H₅₂N₇O₇P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A111000-6X5G	5 g	$492.00 6/EA	Add To Favorites
45-A111000-6X10G	10 g	$982.00 6/EA	Add To Favorites
45-A111000-40X10G	10 g	No Price
45-A111000-6X20G	20 g	$1900.00 6/EA	Add To Favorites
45-A111000-20X40G	40 g	$23170.00 20/EA	Add To Favorites
45-A111000-100G	100 g	$1480.00 1/EA	Add To Favorites
45-A111000-214.6G	214.6 g	$3520.00 1/EA	Add To Favorites
45-A111000-500G	500 g	$6540.00 1/EA	Add To Favorites
45-A111000-1KG	1 kg	$13480.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

λ	conforms (UV/VIS Identity)
assay	≥99% (³¹P-NMR)
	≥99.0% (reversed phase HPLC)
biological source	non-animal source (no BSE/TSE risk)
color	white to off-white
form	powder or granules
impurities	≤0.3 wt. % water content (Karl Fischer)
InChI	1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1
InChI key	GGDNKEQZFSTIMJ-AKWFTNRHSA-N
nucleoside profile	base: deoxyadenosine base protecting group: benzoyl 2' protecting group: none 5' protecting group: DMT deprotection: standard
product line	Proligo Reagents
Quality Level	200
SMILES string	COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
storage temp.	2-8°C
technique(s)	oligo synthesis: suitable
type	for DNA synthesis

General description:

DMT-dA(bz) Phosphoramidite belongs to the group of DNA Phosphoramidites.

Its key features include:

• Exocyclic amine functions are protected by a benzoyl group (dA(bz) anddC(bz)) or isobutyryl group (dG(ib))
• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides

RIDADR	NONH for all modes of transport
WGK Germany	3

Purity	≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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