DMT-dA(bz) Phosphoramidite
SIGMA/A111050 - configured for ÄKTA® and OligoPilot®
Synonym: DMT-dA(bz) Amidite; N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyadenosine, 3′-[2-cyanoethyl N,N-
CAS Number: 98796-53-3
Empirical Formula (Hill Notation): C47H52N7O7P
Molecular Weight: 857.93
MDL Number: MFCD00036314
Linear Formula: C47H52N7O7P
Product Type: Chemical
λ | conforms (UV/VIS Identity) |
assay | ≥99% (31P-NMR) |
≥99.0% (reversed phase HPLC) | |
biological source | non-animal source (no BSE/TSE risk) |
color | white to off-white |
compatibility | configured for ÄKTA® and OligoPilot® |
form | powder or granules |
impurities | ≤0.3 wt. % water content (Karl Fischer) |
InChI | 1S/C47H52N7O7P/c1-32(2)54 |
InChI key | GGDNKEQZFSTIMJ-AKWFTNRHSA |
nucleoside profile | base: deoxyadenosine base protecting group: benzoyl 2' protecting group: none 5' protecting group: DMT deprotection: standard |
product line | Proligo Reagents |
Quality Level | 200 |
SMILES string | COc1ccc(cc1)C(OC[C@H]2O[C |
storage temp. | 2-8°C |
technique(s) | oligo synthesis: suitable |
type | for DNA synthesis |
General description: | Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)).Key features of DNA phosphoramidite :• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides • The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides. The product belongs to ABI Synthesizers synthesizers. |
Legal Information: | ÄKTA is a registered trademark of Cytiva |
Legal Information: | OligoPilot is a registered trademark of Cytiva |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% (31P-NMR); ≥99.0% (reversed phase HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |