Azaserine

SIGMA/A1164 - Hybri-Max^™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

Synonym: O-Diazoacetyl-L-serine

CAS Number: 115-02-6
Empirical Formula (Hill Notation): C₅H₇N₃O₄
Molecular Weight: 173.13
EC Number: 204-061-6
MDL Number: MFCD00036802
Linear Formula: C₅H₇N₃O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A1164-.5MG	0.5 mg	$50.40 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	fungi
form	lyophilized powder
grade	Hybri-Max^™
impurities	endotoxin, tested
InChI	1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
InChI key	MZZGOOYMKKIOOX-VKHMYHEASA-N
mode of action	enzyme \| inhibits
product line	BioXtra
Quality Level	200
SMILES string	N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O
sterility	γ-irradiated
storage temp.	−20°C
technique(s)	cell culture \| hybridoma: suitable

Application:	For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.
Biochem/physiol Actions:	Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.
General description:	Chemical structure: amino acid derivatives
Legal Information:	Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Preparation Note:	Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H301 - H351
Precautionary statements	P201 - P301 + P310 + P330
Hazard Codes	T
Risk Statements	25-40
Safety Statements	53-36/37/39-45
RIDADR	UN 3462 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352207

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