Albumin from human serum
SIGMA/A1653 - lyophilized powder, ≥96% (agarose gel electrophoresis)
Synonym: HSA
CAS Number: 70024-90-7
EC Number: 274-272-6
MDL Number: MFCD00081418
Product Type: Chemical
Human serum albumin is a 66 kDa predominantly monomeric protein with one free sulfhydryl group and 17 intrachain disulfide bonds.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1653-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1653-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1653-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1653-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1653-500MG
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| assay | ≥96% (agarose gel electrophoresis) |
| biological source | human |
| form | lyophilized powder |
| impurities | HIV I and HIVII, HCV and HBsAg, tested negative |
| InChI | 1S/C3F8/c4-1(5,2(6,7)8)3( |
| InChI key | QYSGYZVSCZSLHT-UHFFFAOYSA |
| mol wt | monomer calculated mol wt 66478 Da |
| Quality Level | 300  |
| solubility | H2O: soluble 50 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | ELISA: suitable |
| tissue culture: suitable | |
| western blot: suitable | |
| UniProt accession no. | P02768  |
| Application: | Albumin from human serum has been used: • in cyclophilin isomerase assay • as a component in blocking solution for immunogold quantification of amino acids and proteins in complex subcellular compartments • in G-pseudotyped HIV (PHIV) assay mixture to study its effect on GSK364735 antiviral potency |
| Application: | Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery. |
| Biochem/physiol Actions: | Albumin serves as a protein repository and functions as a binding and transport protein. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. |
| Biochem/physiol Actions: | Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | Albumin (ALB) constitutes 25% of the proteins produced by the liver. It is a protein of a single polypeptide chain with a thiol group. The ALB gene is mapped to human 4q13.3. |
| Other Notes: | View more information on human serum albumin . |
| Packaging: | 1, 5, 10, 50, 100 g in poly bottle |
| Packaging: | 500 mg in poly bottle |
| Quality: | Remainder mostly globulins |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥96% (agarose gel electrophoresis) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |