Aminophylline
SIGMA/A1755 - ≥98%, powder
Synonym: (Theophylline)2 ยท Ethylenediamine; 3,7-
CAS Number: 317-34-0
Empirical Formula (Hill Notation): C7H8N4O2 · 0.5C2H8N2
Molecular Weight: 210.21
EC Number: 206-264-5
MDL Number: MFCD00013221
Linear Formula: C7H8N4O2 · 0.5C2H8N2
Product Type: Chemical
assay | ≥98% |
color | white to off-white |
form | powder |
InChI | 1S/2C7H8N4O2.C2H8N2/c2*1- |
InChI key | FQPFAHBPWDRTLU-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NCCN.CN1C(=O)N(C)c2nc[nH] |
solubility | alcohol: insoluble |
H2O: 50 mg/mL (solutions should be freshly prepared.) | |
storage temp. | −20°C |
Application: | Aminophylline has been used: • as a positive control in the selective inhibitor of nuclear export, KPT-350 zebrafish dosing experiments • as a positive control for the determination of the spasmolytic activity of C. aeruginosa extracts • as a phosphodiesterase (PDE) inhibitor in inhibitor studies to quantify its potency to inhibit PDE4A1A and PDE3A enzyme in an assay |
Biochem/physiol Actions: | Aminophylline is a methylxanthine compound containing theophylline andethylenediamine in a ratio of 2:1. It acts as a bronchodilator and is used to treat chronic lung diseases like asthma, bronchitis, or emphysema. |
Biochem/physiol Actions: | Non-selective phosphodiesterase (PDE) inhibitor. Antiepileptic drug |
Packaging: | 25, 100 g in poly bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% |
Storage Temp. | −20°C |
UNSPSC | 41106305 |