Synonym: 6-AU; 1,2,4-Triazine-3,5(2H,4H)-dione; 3,5-Dihydroxy-1,2,4-triazine; 6-Aza-2,4-dihydroxypyrimidine
CAS Number: 461-89-2
Empirical Formula (Hill Notation): C3H3N3O2
Molecular Weight: 113.07
EC Number: 207-318-0
MDL Number: MFCD00006456
Linear Formula: C3H3N3O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A1757-5G
assay |
≥98% |
form |
powder |
InChI |
1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8) |
InChI key |
SSPYSWLZOPCOLO-UHFFFAOYSA-N |
mp |
274-275 °C (lit.) |
Quality Level |
100 |
SMILES string |
O=C1NN=CC(=O)N1 |
solubility |
1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow-green |
Application: |
6-Azauracil has been used as a transcriptional inhibitor to study its effects on the deletion of termination and polyadenylation protein (Tpa1) and Mag1 on cell viability. It has also been used as an orotidine-5′-monophosphate decarboxylase (OMPdecase) inhibitor in minimal media for determining the OMPdecase activity. |
Biochem/physiol Actions: |
6-Azauracil (6-AU) is a pyrimidine analog of uracil and exhibits antitumor activity. It inhibits the growth of various microorganisms by depleting intracellular guanosine triphosphate (GTP) and uridine triphosphate (UTP) nucleotide pools. |
Packaging: |
5 g in poly bottle |
Hazard Codes |
Xi |
Risk Statements |
36/37/38 |
Safety Statements |
26-36 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% |
mp |
274-275 °C (lit.) |
UNSPSC |
41106305 |