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Amikacin disulfate salt

SIGMA/A1774 - potency: 674-786 μg per mg (as amikacin base)

Synonym: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate; Antibiotic BB-K8 sulfate

CAS Number: 39831-55-5
Empirical Formula (Hill Notation): C22H43N5O13 · 2H2SO4
Molecular Weight: 781.76
EC Number: 254-648-6
MDL Number: MFCD00167475
Linear Formula: C22H43N5O13 · 2H2SO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A1774-250MG 250 mg
 $59.60
1/EA		 Add To Favorites
45-A1774-1G 1 g
 $183.00
1/EA		 Add To Favorites
45-A1774-5G 5 g
 $782.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum Gram-negative bacteria
  mycobacteria
biological source synthetic
color white to off-white
form powder or crystals
InChI 1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1
InChI key FXKSEJFHKVNEFI-GCZBSULCSA-N
mode of action protein synthesis | interferes
potency 674-786 μg per mg (as amikacin base)
Quality Level 200 
SMILES string OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
storage temp. 2-8°C
Application: Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .
Biochem/physiol Actions: Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.
General description: Chemical structure: aminoglycoside
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 51101500

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