Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit
SIGMA/A1976 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Aβ 42
MDL Number: MFCD04040171
Product Type: Chemical
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 4 kDa |
| packaging | antibody small pack of 25 μg |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | rat, human, mouse |
| storage temp. | −70°C |
| target post-translational modification | proteolytically cleaved (Ala42) |
| technique(s) | dot blot: 0.05-1 μg/mL |
| immunoblotting: suitable | |
| immunohistochemistry: suitable | |
| immunoprecipitation (IP): suitable | |
| indirect ELISA: 1:200 | |
| radioimmunoassay: 1:200 | |
| UniProt accession no. | P05067  |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) |
| Application: | Rabbit anti-Aβ42 is suitable for use in immunoblot, immunohistochemistry, immunoprecipitation, RIA, ELISA and dot blot applications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients. |
| General description: | Rabbit anti-amyloid peptide β, cleavage site 42 (Aβ42) antibody binds to human, mouse and rat Aβ42. |
| Immunogen: | synthetic peptide of approximately 10 amino acid residues at the C-terminus of Aβ42. |
| Physical form: | Solution in phosphate buffer, pH 7.4, containing approximately 25 μg of antibody. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −70°C |
| UNSPSC | 12352203 |