AM6545

SIGMA/A1987 - ≥98% (HPLC)

Synonym: 5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide

CAS Number: 1245626-05-4
Empirical Formula (Hill Notation): C₂₆H₂₃Cl₂N₅O₃S
Molecular Weight: 556.46
MDL Number: MFCD19053178
Linear Formula: C₂₆H₂₃Cl₂N₅O₃S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A1987-5MG	5 mg	$304.00 1/EA	Add To Favorites
45-A1987-25MG	25 mg	$968.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to off-white
form	powder
InChI	1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34)
InChI key	XBHQLFVDGLPBCK-UHFFFAOYSA-N
Quality Level	100
SMILES string	Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(cc3)C#CCCC#N)C(=O)NN4CCS(=O)(=O)CC4
solubility	DMSO: >25 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	AM6545 helps in decreasing the development of albuminuria, inflammation and expression of markers of fibrosis. It also helps in the down-regulation of nephrin and podocin. It has the ability to repress the ingestion of food and food-reinforced behaviour.
Biochem/physiol Actions:	AM6545 is a peripheral CB1 cannabinoid receptor antagonist and appetite suppressant.
Features and Benefits:	This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	AM6545 is a cannabinoid (CB1) receptor antagonist.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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