L-Arginine-7-amido-4-methylcoumarin hydrochloride

SIGMA/A2027 - cathepsin H substrate

Synonym: Arginine 4-methyl-7-coumarylamide

CAS Number: 69304-16-1
Empirical Formula (Hill Notation): C₁₆H₂₁N₅O₃
Molecular Weight: 331.37
MDL Number: MFCD00058184
Linear Formula: C₁₆H₂₁N₅O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A2027-5MG	5 mg	$173.00 1/EA		Add To Favorites
45-A2027-25MG	25 mg	$565.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (TLC)
form	powder
InChI	1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1
InChI key	PFLMUQNBZRXRHD-YDALLXLXSA-N
Quality Level	200
SMILES string	Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)CCCNC(N)=N)ccc12
solubility	acetic acid: water (1:1): 50 mg/mL, clear, colorless to light yellow
storage temp.	−20°C

Application:	L-Arginine-7-amido-4-methylcoumarin hydrochloride has been used as a substrate for cathepsin H from rat muscle homogenate and sarcoplasmic extract. It has also been used as a substrate for arginine amino-peptidase from Daphnia homogenates and recombinant aminopeptidase from Toxoplasma gondii.
Biochem/physiol Actions:	L-Arginine-7-amido-4-methylcoumarin hydrochloride is a protease substrate. It is a specific substrate for cathepsin H and not for cathepsin L and B.
Packaging:	25 mg in poly bottle
Packaging:	5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (TLC)
Storage Temp.	−20°C
UNSPSC	12352204

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