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DMT-2′O-TBDMS-rA(bz) Phosphoramidite

SIGMA/A211030 - configured for ABI

Synonym: DMT-2’O-TBDMS-rA(bz) Amidite; N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS Number: 104992-55-4
Empirical Formula (Hill Notation): C53H66N7O8PSi
Molecular Weight: 988.19
MDL Number: MFCD00080297
Linear Formula: C53H66N7O8PSi
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A211030-1G 1 g
 $93.10
1/EA		 Add To Favorites

 

λ conforms (UV/VIS Identity)
assay ≥99% (31P-NMR)
  ≥99.0% (reversed phase HPLC)
biological source non-animal source (no BSE/TSE risk)
color white to off-white
compatibility configured for ABI
form powder
impurities ≤0.3% water content (Karl Fischer)
  ≤0.5% P(III) Impurities 100-169ppm (31P-NMR)
  ≤0.5% single Impurity (reversed phase HPLC)
  ≤3% residual Solvent content
InChI 1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1
InChI key FFXHNCNNHASXCT-RFMFGJHUSA-N
nucleoside profile base: adenosine
base protecting group: benzoyl
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard
product line Proligo Reagents
Quality Level 300 
SMILES string COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
storage temp. −20°C
suitability conforms to structure for H-NMR
  conforms to structure for LC-MS
technique(s) oligo synthesis: suitable
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (31P-NMR); ≥99.0% (reversed phase HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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