3′-Azido-3′-deoxythymidine
SIGMA/A2169 - ≥98% (HPLC)
Synonym: AZT; Azidothymidine; ZDV; Zidovudine
CAS Number: 30516-87-1
Empirical Formula (Hill Notation): C10H13N5O4
Molecular Weight: 267.24
MDL Number: MFCD00006536
Linear Formula: C10H13N5O4
Product Type: Chemical
assay | ≥98% (HPLC) |
form | powder |
InChI | 1S/C10H13N5O4/c1-5-3-15(1 |
InChI key | HBOMLICNUCNMMY-XLPZGREQSA |
mp | 113-115 °C (lit.) |
Quality Level | 200 |
SMILES string | CC1=CN([C@H]2C[C@H](N=[N+ |
solubility | H2O: 50 mg/mL |
storage temp. | −20°C |
Application: | 3′-Azido-3′-deoxythymidin |
Biochem/physiol Actions: | Azidothymidine (AZT), a thymidine analogue, is a reverse transcriptase inhibitor against the HIV-1 virus. Azidothymidine has been shown to decrease CRISPR-mediated homology-directed repair (HDR) efficiency. |
Biochem/physiol Actions: | Reverse transcriptase inhibitor active against HIV-1 virus. |
Features and Benefits: | This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 1 g in glass bottle |
Packaging: | 100, 250 mg in glass bottle |
Packaging: | 25 mg in glass insert |
Hazard Codes | Xn |
Risk Statements | 40 |
Safety Statements | 36/37/39-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
mp | 113-115 °C (lit.) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |