6-Aminocaproic acid
SIGMA/A2504 - ≥99% (titration), powder
Synonym: ε-Aminocaproic acid; 6-Aminohexanoic acid; EACA
CAS Number: 60-32-2
Empirical Formula (Hill Notation): C6H13NO2
Molecular Weight: 131.17
EC Number: 200-469-3
MDL Number: MFCD00008238
Linear Formula: H2N(CH2)5CO2H
Product Type: Chemical
assay | ≥99% (titration) |
biological source | synthetic |
color | white |
form | powder |
InChI | 1S/C6H13NO2/c7-5-3-1-2-4- |
InChI key | SLXKOJJOQWFEFD-UHFFFAOYSA |
mp | 207-209 °C (dec.) (lit.) |
Quality Level | 300 |
SMILES string | NCCCCCC(O)=O |
solubility | H2O: 50 mg/mL |
technique(s) | cell culture | mammalian: suitable |
Application: | EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature. |
Biochem/physiol Actions: | EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carboxypeptidase, plasmin, and plasminogen activator. |
Biochem/physiol Actions: | Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B. |
Packaging: | 1 kg in poly bottle |
Packaging: | 25, 100, 500 g in poly bottle |
Packaging: | 5 kg in poly drum |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | 404.6 - 408.2 °F |
Flash Point(C) | 207 - 209 °C |
Purity | ≥99% (titration) |
mp | 207-209 °C (dec.) (lit.) |
UNSPSC | 12352202 |