AMG 9810
SIGMA/A2731 - ≥98% (HPLC), powder
Synonym: 2E-
CAS Number: 545395-94-6
Empirical Formula (Hill Notation): C21H23NO3
Molecular Weight: 337.41
MDL Number: MFCD00955103
Linear Formula: C21H23NO3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C21H23NO3/c1-21(2,3)16 |
InChI key | GZTFUVZVLYUPRG-IZZDOVSWSA |
originator | Amgen |
Quality Level | 100 |
SMILES string | CC(C)(C)c1ccc(C=CC(=O)N |
solubility | DMSO: >5 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | AMG 9810 is a potent, non-vanilloid, antagonist of the TRPV1 receptor. IC50 = 17 nM. |
Biochem/physiol Actions: | AMG 9810 is the cinnamide TRPV1 (vanilloid receptor 1) antagonist, that can prevent eye wiping behavior, stimulated by capsaicin and can inverse hyperalgesia in an animal model of inflammatory pain. It possesses antihyperalgesic properties. |
Features and Benefits: | This compound was developed by Amgen . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
Packaging: | 10, 50 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H413 |
Precautionary statements | P264 - P270 - P273 - P301 + P312 - P501 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352203 |