Atractylenolide I
SIGMA/A2737 - ≥98% (HPLC)
CAS Number: 73069-13-3
Empirical Formula (Hill Notation): C15H18O2
Molecular Weight: 230.30
MDL Number: MFCD09037395
Linear Formula: C15H18O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A2737-10MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: A2737-50MG
This image depicts SKU: A2737-50MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| form | powder or crystals |
| InChI | 1S/C15H18O2/c1-9-5-4-6-15 |
| InChI key | ZTVSGQPHMUYCRS-SWLSCSKDSA |
| Quality Level | 100  |
| SMILES string | C=C1CCC[C@@](C=C2O3)(C)[C |
| solubility | methanol: 1 mg/mL, clear, colorless |
| storage temp. | 2-8°C |
| Application: | Atractylenolide I is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide I may be used and studied as a postitive modulator of GABA-induced chloride currents I(GABA) and as an inhibitor of aromatases. Atractylenolide I may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma. |
| Biochem/physiol Actions: | Atractylenolide I has been reported to have an anti-inflammatory activity due to its inhibitory effect on tumor necrosis factor-α (TNF-α) and the production of nitric oxide (NO). It also shows anti-cancer nature, thereby being used in the management of gastric cancer cachexia symptoms. Additionally, it has anti-angiogenic, pro-oxidative and cytotoxic characteristics. |
| Biochem/physiol Actions: | Phytochemical from Traditional Chinese Medicine herbal preparations. Atractylenolide I is an anti-inflammatory that is reported to inhibit angiogenesis. |
| General description: | Atractylenolide I is one of the active ingredients of Rhizoma Atractylodes macrocephala which is obtained from the dried root and stem of Atractylodes Macrocephala Koidz. It is a sesquiterpene compound of hydrophobic nature. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 50 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 339.6 °F |
| Flash Point(C) | 170.87 °C |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |