Astilbin from Engelhardtia roxburghiana

SIGMA/A2862 - ≥98%

Synonym: Astilbin; Dihydroquercetin 3-rhamnoside; Taxifolin 3-rhamnoside

CAS Number: 29838-67-3
Empirical Formula (Hill Notation): C₂₁H₂₂O₁₁
Molecular Weight: 450.39
MDL Number: MFCD20274680
Linear Formula: C₂₁H₂₂O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A2862-10MG	10 mg	$199.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98%
form	powder
InChI	1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1
InChI key	ZROGCCBNZBKLEL-MFSALPCASA-N
Quality Level	100
SMILES string	O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4
solubility	H₂O: 1 mg/mL, clear, colorless
storage temp.	2-8°C

Application:	Astilbin from Engelhardtia roxburghiana, a flavonoid phytochemical with antibacterial activity, may be used to study its pharmacology and the effects of its antiproliferative activities versus a variety of cell types.
Biochem/physiol Actions:	Astilbin exerts various biological activities such as anti-oxidative, anti-bacterial, and inhibition of contact hypersensitivity. Also, it shows insecticidal, anti-oedematogenic, antinociceptive and antidepressant properties. It has an inhibitory effect on the aldose reductase enzyme, the accumulation of sorbitol, and a protective effect on the liver. Astilbin is helpful against autoimmune diseases such as rheumatoid arthritis due to its ability to reduce matrix metalloproteinase (MMP) activity and Nitric oxide production in T lymphocytes.
Biochem/physiol Actions:	Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.
General description:	Astilbin belongs to the class of dihydroflavanol compounds and is the chief biologically active component of Rhizoma Smilacis Glabrae (RSG) extract. RSG is obtained from the dried rhizome of Smilax Glabra Roxb.
Packaging:	10 mg in glass insert
Packaging:	50 mg in poly bottle

Symbol	GHS09
Signal word	Warning
Hazard statements	H400
Precautionary statements	P273
Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	2-8°C
UNSPSC	12352200

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