Atractylenolide III

SIGMA/A2987 - ≥98% (HPLC)

Synonym: 8β-Hydroxyasterolide; Codonolactone

CAS Number: 73030-71-4
Empirical Formula (Hill Notation): C₁₅H₂₀O₃
Molecular Weight: 248.32
MDL Number: MFCD00238543
Linear Formula: C₁₅H₂₀O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A2987-10MG	10 mg	$377.00 1/EA	Add To Favorites
45-A2987-50MG	50 mg	$1220.00 1/EA	Add To Favorites

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This image depicts SKU: A2987-50MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98% (HPLC)
biological source	Atractylodes macrocephala Koidz.
color	white to off-white
form	powder or crystals
InChI	1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1
InChI key	FBMORZZOJSDNRQ-GLQYFDAESA-N
Quality Level	100
SMILES string	CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C[C@]2(O)OC1=O
solubility	methanol: 1 mg/mL, clear, colorless
storage temp.	2-8°C

Application:	Atractylenolide III has been used to examine its effects on the energy metabolism in the skeletal muscles of mouse.
Application:	Atractylenolide III, a sesquiterpenoid, is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide III may be used and studied as an inhibitor of aromatases and inducer of apoptosis. Atractylenolide III may be used to study its sonic hedgehog pathway dependent mechanism of action as an inducer of chondrogenic differentiation. Atractylenolide III may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.
Biochem/physiol Actions:	Atractylenolide III has been shown to possess anti-inflammatory effects and also offers gastroprotection. It also shows acaricidal properties and hence has the potential to be used as an agent for the control of dust mites. Atractylenolide III is capable of regulating the secretion and expression of Interleukin-6, thereby mediating the immune response caused by mast cells.
Biochem/physiol Actions:	Atractylenolide III possesses anti-inflammatory and anticancer properties.
General description:	Atractylenolide III is a biologically active sesquiterpene compound, extracted from the roots of Atractylodes macrocephala Koidzumi.
Packaging:	10 mg in glass insert
Packaging:	50 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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