Adenosine 2′,5′-diphosphate–Agarose
SIGMA/A3515 - lyophilized powder
MDL Number: MFCD00161940
Product Type: Chemical
extent of labeling | 1-5 μmol per mL |
form | lyophilized powder |
matrix | cross-linked 4% beaded agarose |
matrix activation | cyanogen bromide |
matrix attachment | N-6 |
matrix spacer | 8 atoms |
Quality Level | 200 |
storage temp. | −20°C |
Application: | Adenosine 2′,5′-diphosphate Agarose (2′,5′-ADP agarose) has been used to study NADPH-cytochrome P450 oxidoreductase (CPR), which plays an important role in the insecticide resistance of Anopheles gambiae (a major malaria vector). In particular, Anopheles gambiae CPR (AgCPR) displayed a decreased affinity to adenosine 2′,5′-phosphate when compared to human CPR (hCPR) determined by isothermal titration calorimetry. This may be important for the development of more advanced insecticides that selectively target mosquito CPR. |
Packaging: | 1, 5, 25 mL in poly bottle |
Physical form: | Lyophilized powder stabilized with lactose |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 41106500 |