Anti-Human IgG (whole molecule)−Agarose antibody produced in goat
SIGMA/A3543 - IgG fraction of antiserum, PBS suspension
MDL Number: MFCD00162452
Product Type: Chemical
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| antibody form | IgG fraction of antiserum |
| antibody product type | secondary antibodies |
| biological source | goat |
| capacity | 1 mg/mL binding capacity |
| clone | polyclonal |
| conjugate | agarose conjugate |
| extent of labeling | ~2.4 mg Ab per mL |
| form | PBS suspension |
| Quality Level | 200  |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | immunoelectrophoresis: suitable |
| Application: | Anti-human IgG (whole molecule) is suitable for immunoelectrophoresis. Antibody depletion from normal human serum was carried out by treating diluted serum with 50 microl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 °. |
| Application: | Antibody depletion from normal human serum was carried out by treating diluted serum with 50 μl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 degrees. |
| Biochem/physiol Actions: | Anti-human IgG recognizes human IgG (whole molecules). Goat anti-human is purified by ion exchange chromatography and then covalently bound to agarose. |
| Biochem/physiol Actions: | IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. |
| Immunogen: | Pooled normal human serum |
| Physical form: | Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37-60 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |