Synonym: 9-Bromo-7,12-dihydro-pyrido[3′,2′:2,3]azepino[4,5-b]indol-6(5H)-one
CAS Number: 676596-65-9
Empirical Formula (Hill Notation): C15H10BrN3O
Molecular Weight: 328.16
MDL Number: MFCD09037522
Linear Formula: C15H10BrN3O
Product Type: Chemical
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This image depicts A3734-1MG.
| assay |
≥97% (HPLC) |
| color |
gray-brown |
| form |
powder |
| InChI |
1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20) |
| InChI key |
NTSBZVCEIVPKBJ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=C1CC2=C(NC3=C2C=C(Br)C=C3)C4=C(C=CC=N4)N1 |
| solubility |
DMSO: >10 mg/mL |
| storage condition |
protect from light |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
1-Azakenpaullone (AZP) can stimulate the transcription of β-catenin-related genes. This compound can induce the multiplication and replication of β cell. |
| Biochem/physiol Actions: |
1-Azakenpaullone is a cell permeable, potent, selective inhibitor of glycogen synthase kinase 3β (GSK3β) with 100-fold less cross-reactivity against CDKs. |
| Biochem/physiol Actions: |
1-Azakenpaullone is a cell permeable, potent, selective inhibitor of glycogen synthase kinase 3β (GSK3β) with 100-fold less cross-reactivity against CDKs. 1-Azakenpaullone can be used together with BIO and CHIR99021 as "gold standards" for GSK3 inhibition. |
| Disclaimer: |
air sensitive |
| Packaging: |
1, 5 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥97% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |