R-(−)-Apomorphine hydrochloride hemihydrate
SIGMA/A4393 - calcined, ≥98% (TLC)
CAS Number: 41372-20-7
Empirical Formula (Hill Notation): C17H17NO2 · HCl · 0.5H2O
Molecular Weight: 312.79
EC Number: 206-243-0
MDL Number: MFCD00150904
Linear Formula: C17H17NO2 · HCl · 1/2H2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A4393-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A4393-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A4393-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A4393-5G
| assay | ≥98% (TLC) |
| color | white to gray |
| form | (Powder to Crystalline Powder) |
| calcined | |
| InChI | 1S/2C17H17NO2.2ClH.H2O/c2 |
| InChI key | CXWQXGNFZLHLHQ-DPFCLETOSA |
| mp | 285-287 °C (lit.) |
| Quality Level | 200  |
| SMILES string | Cl[H].Cl[H].[H]O[H].[H][C |
| solubility | H2O: ~10 mg/mL, clear, yellow-green |
| storage condition | protect from light |
| under inert gas |
| Application: | R-(-)-Apomorphine hydrochloride hemihydrate has been used as a dopamine receptor agonist to study its effects of rotational behavior in rat models of Parkinson′s disease. |
| Biochem/physiol Actions: | R-(−)-Apomorphine acts as a non-selective D1 and D2 dopamine receptor agonist. It shows therapeutic effects against Parkinson′s disease and male erectile dysfunction. R-(−)-Apomorphine also shows neuroprotective, radical scavenging, and emetic effects. Apomorphine stimulates the brain chemoreceptor trigger zone. It stimulates the chemoreceptor trigger zone in the brain. |
| Packaging: | 1, 5 g in glass bottle |
| Packaging: | 100, 250 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 285-287 °C (lit.) |
| UNSPSC | 12352210 |