AMPK (α1/β1/γ3), active, His tagged human
SIGMA/A4486 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: HAMPKb; MGC17785; MGC33776; MGC57364; PRKAA1; PRKAB1; PRKAG3
Product Type: Chemical
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| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | A1 subunit ~68 kDa |
| B1 subunit ~38 kDa | |
| G3 subunit ~51 kDa | |
| product line | PRECISIO® Kinase |
| Quality Level | 200  |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 157-213 nmol/min·mg |
| storage temp. | −70°C |
| UniProt accession no. | Q13131  |
| Q9UGI9 |
|
| Q9Y478 |
| Biochem/physiol Actions: | AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutary |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol. |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H360D |
| Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 61 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 157-213 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |