L-Arginine monohydrochloride
SIGMA/A4599
Synonym: (S)
CAS Number: 1119-34-2
Empirical Formula (Hill Notation): C6H14N4O2 · HCl
Molecular Weight: 210.66
EC Number: 214-275-1
MDL Number: MFCD00064550
Linear Formula: C6H14N4O2 · HCl
Product Type: Chemical
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| anion traces | chloride (Cl-): 16.58-17.00% |
| sulfate (SO42-): ≤0.020% | |
| application(s) | pharmaceutical (small molecule) |
| assay | ≥98.5% |
| biological source | non-animal source |
| cation traces | As: ≤1.0 ppm |
| heavy metals: ≤10 ppm | |
| NH4+: ≤0.02% | |
| density | 1.42 g/cm3 at 20 °C |
| foreign activity | cytotoxicity, tested |
| form | crystalline powder |
| impurities | endotoxin, heavy metals, residual solvents, tested |
| InChI | 1S/C6H14N4O2.ClH/c7-4(5(1 |
| InChI key | KWTQSFXGGICVPE-WCCKRBBISA |
| Quality Level | 400  |
| SMILES string | Cl[H].N[C@@H](CCCNC(N)=N) |
| solubility | H2O: 100 mg/mL |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility. |
| Biochem/physiol Actions: | Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service. |
| General description: | To request documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the documentation for this product requires a confidentiality disclosure agreement. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% |
| Density | 1.42 g/cm3 at 20 °C |
| UNSPSC | 12352209 |