Bovine Serum Albumin
SIGMA/A4737 - lyophilized powder, protease, essentially free, ≥98% (agarose gel electrophoresis)
Synonym: Albumin from bovine serum; Albumin bovine serum; BSA; Bovine albumin
CAS Number: 9048-46-8
EC Number: 232-936-2
MDL Number: MFCD00130384
Product Type: Chemical
assay | ≥98% (agarose gel electrophoresis) |
biological source | bovine |
foreign activity | protease, essentially free |
form | lyophilized powder |
impurities | ≤8.0% water (Karl Fischer) |
mol wt | ~66 kDa |
origin | New Zealand origin |
packaging | poly bottle of |
pH | 4.8-7.5 |
Quality Level | 200 |
solubility | H2O: soluble 50 mg/mL |
storage temp. | 2-8°C |
technique(s) | ligand binding assay: suitable |
UniProt accession no. | P02769 |
Application: | Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry. |
Biochem/physiol Actions: | Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals. |
Biochem/physiol Actions: | Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies. |
General description: | The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands. |
Packaging: | 1 kg in poly bottle |
Packaging: | 1, 25, 100 g in poly bottle |
Preparation Note: | Purified by chromatography |
Preparation Note: | Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration. |
Preparation Note: | Sourced and manufactured in New Zealand |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (agarose gel electrophoresis) |
Storage Temp. | 2-8°C |
UNSPSC | 12352202 |