Aconitase from porcine heart
SIGMA/A5384
Synonym: Aconitate hydratase; Citrate (isocitrate) hydrolyase
CAS Number: 9024-25-3
MDL Number: MFCD00130335
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| biological source | Porcine heart |
| form | solid |
| mol wt | ~66 kDa by gel filtration |
| Quality Level | 200  |
| storage temp. | −20°C |
| Analysis Note: | Crude preparation containing aconitase activity |
| Application: | Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases . |
| Biochem/physiol Actions: | Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity. |
| Other Notes: | One unit will convert 1.0 μmole of citrate (via cis-aconitate) to isocitrate per min at pH 7.4 at 25 °C. |
| Packaging: | 150, 250 mg in serum bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 4.2.1.3 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |