L-Aspartic acid
SIGMA/A5474
Synonym: (S)-(+)-Aminosuccinic acid; (S)-Aminobutanedioic acid
CAS Number: 56-84-8
Empirical Formula (Hill Notation): C4H7NO4
Molecular Weight: 133.10
EC Number: 200-291-6
MDL Number: MFCD00002616
Linear Formula: HO2CCH2CH(NH2)CO2H
Product Type: Chemical
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| application(s) | pharmaceutical (small molecule) |
| assay | ≥98.5% |
| biological source | non-animal source |
| foreign activity | cytotoxicity, tested |
| form | crystalline powder |
| impurities | endotoxin, heavy metals, trace metals, residual solvents, tested |
| InChI | 1S/C4H7NO4/c5-2(4(8)9)1-3 |
| InChI key | CKLJMWTZIZZHCS-REOHCLBHSA |
| mp | >300 °C (dec.) (lit.) |
| Quality Level | 400  |
| SMILES string | N[C@@H](CC(O)=O)C(O)=O |
| solubility | 1 M HCl: 50 mg/mL |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Aspartic acid is one of the 23 proteinogenic amino acids. It is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. |
| Biochem/physiol Actions: | Principal neurotransmitter for fast synaptic excitation. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service. |
| General description: | To request documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the documentation for this product requires a confidentiality disclosure agreement. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% |
| mp | >300 °C (dec.) (lit.) |
| UNSPSC | 12352209 |