Azoxymethane
SIGMA/A5486 - 13.4 M, ≥98%
Synonym: AOM
CAS Number: 25843-45-2
Empirical Formula (Hill Notation): C2H6N2O
Molecular Weight: 74.08
MDL Number: MFCD00126912
Linear Formula: CH3N=N(→O)CH3
Product Type: Chemical
| application(s) | genomic analysis |
| assay | ≥98% |
| bp | 97-99 °C (lit.) |
| color | colorless |
| composition | methylene chloride, ≤1% (solvent) |
| concentration | 13.4 M |
| density | 0.991 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C2H6N2O/c1-3-4(2)5/h1- |
| InChI key | DGAKHGXRMXWHBX-ONEGZZNKSA |
| Quality Level | 200  |
| SMILES string | CN=[N+](/C)[O-] |
| storage condition | ( |
| storage temp. | −20°C |
| Application: | Azoxymethane (AOM), a gene mutation agent, may be used with dextran sulfate sodium (DSS) to create cancer models in laboratory animals which can be used to study mechanisms of cancer progression and chemoprevention. |
| Biochem/physiol Actions: | Carcinogen that induces O6-methylguanine adducts in DNA leading to G→A transitions. Induces tumorigenesis in the colon of laboratory animals and is used to study the mechanism of cancer progression and chemoprevention. |
| Features and Benefits: | Versatile and adaptable for a wide variety of laboratory and research applications. |
| General description: | Azoxymethane (AOM) is a potent laboratory chemical used to study cancer initiation, progression, and prevention, particularly in the colon. It acts as both a carcinogen, triggering tumor formation, and a gene mutation agent, causing specific alterations in DNA. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Other Notes: | It is critical to determine the correct dosage of Azoxymethane for the experimental design to avoid premature death of laboratory animals. |
| Packaging: | 25, 100 mg in ampule |
| Symbol |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H226 - H300 - H315 - H319 - H350 |
| Precautionary statements | P201 - P202 - P210 - P301 + P310 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 45-46-10-25-36/38 |
| Safety Statements | 53-26-45 |
| RIDADR | UN 1992 6.1(3) / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 75.2 °F |
| Flash Point(C) | 24 °C |
| Purity | ≥98% |
| bp | 97-99 °C (lit.) |
| Density | 0.991 g/mL at 25 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352124 |