Amlodipine besylate
SIGMA/A5605 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 111470-99-6
Empirical Formula (Hill Notation): C20H25ClN2O5 · C6H5SO3H
Molecular Weight: 567.05
MDL Number: MFCD00887594
Linear Formula: C20H25ClN2O5 · C6H5SO3H
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white |
form | powder |
InChI | 1S/C20H25ClN2O5.C6H6O3S/c |
InChI key | ZPBWCRDSRKPIDG-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | OS(=O)(=O)c1ccccc1.CCOC(= |
solubility | DMSO: ≥20 mg/mL |
Application: | Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
Biochem/physiol Actions: | Amlodipine is an L-type calcium channel blocker. Amlodipine belongs to a class of cardiovascular drugs, which act at the voltage gated calcium channel of the CaV1, or L-type, class. Amlodipine also has antihypertensive and antianginal effects. Its activity resides mainly in the (-)-isomer. Amlodipine inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
Features and Benefits: | This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 10, 50 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
UNSPSC | 12352200 |