Synonym: (2-[2-[4-(o-Methoxyphenyl)piperazin-1-yl]ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolinedione dihydrochloride hydrate
CAS Number: 67339-62-2 (free base)
Empirical Formula (Hill Notation): C24H29N3O3·2HCl · xH2O
Molecular Weight: 480.43 (anhydrous basis)
MDL Number: MFCD16875414
Linear Formula: C24H29N3O3·2HCl · xH2O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to off-white |
| form |
powder |
| InChI |
1S/C24H29N3O3.2ClH.H2O/c1-24(2)19-9-5-4-8-18(19)22(28)27(23(24)29)17-14-25-12-15-26(16-13-25)20-10-6-7-11-21(20)30-3;;;/h4-11H,12-17H2,1-3H3;2*1H;1H2 |
| InChI key |
KWVGFMWBNZTADI-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O.Cl.Cl.COc1ccccc1N2CCN(CC2)CCN3C(=O)c4ccccc4C(C)(C)C3=O |
| solubility |
H2O: >5 mg/mL |
| storage temp. |
2-8°C |
| Application: |
ARC 239 is a potent α-adrenoceptor blocking drug, competitively antagonizing pressor responses to adrenaline and inhibiting pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium. |
| Biochem/physiol Actions: |
ARC 239 is a selective α-2B adrenergic blocker. |
| Biochem/physiol Actions: |
ARC 239 is a selective α-2B adrenergic blocker. Although ARC-239, like prazosin, also has some alpha-1 antagonist activity, it is used most commomly to differentiate alpha-2A/D from alpha-2B and alpha-2C subtypes rather than for any alpha-1 inhibition.. |
| Packaging: |
5 mg in glass bottle |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
GHS07,GHS09