γ-Aminobutyric acid
SIGMA/A5835 - BioXtra, ≥99%
Synonym: 3-Carboxypropylamine; 4-Aminobutanoic acid; GABA; Piperidic acid; Piperidinic acid
CAS Number: 56-12-2
Empirical Formula (Hill Notation): C4H9NO2
Molecular Weight: 103.12
EC Number: 200-258-6
MDL Number: MFCD00008226
Linear Formula: NH2(CH2)3COOH
Product Type: Chemical
| anion traces | chloride (Cl-): <0.04% |
| sulfate (SO42-): <0.05% | |
| assay | ≥99% |
| cation traces | Al: <5 mg/kg |
| Ca: <20 mg/kg | |
| Cu: <5 mg/kg | |
| Fe: <5 mg/kg | |
| K: <50 mg/kg | |
| Mg: <50 mg/kg | |
| Na: <70 mg/kg | |
| NH4+: <500 mg/kg | |
| Pb: <10 mg/kg | |
| Zn: <5 mg/kg | |
| color | white |
| form | powder |
| ign. residue | <0.1% |
| impurities | <0.0005% Phosphorus (P) |
| <0.1% Insoluble matter | |
| InChI | 1S/C4H9NO2/c5-3-1-2-4(6)7 |
| InChI key | BTCSSZJGUNDROE-UHFFFAOYSA |
| mp | 195 °C (dec.) (lit.) |
| product line | BioXtra |
| Quality Level | 200  |
| SMILES string | NCCCC(O)=O |
| solubility | H2O: 0.5 M at 20 °C, clear, colorless |
| technique(s) | ligand binding assay: suitable |
| Application: | γ-Aminobutyric acid (GABA) has been used to treat dorsal root ganglion neurons for electrophysiological recordings studies to test its effect on neuropathic pain in rats. It has also been used to test its protective effects in an ex vivo machine perfusion system of small-for-size grafts (SFSG) injury model. |
| Biochem/physiol Actions: | Major inhibitory neurotransmitter in brain; GABAA and GABAB receptor agonist; increases Cl− conductance. |
| Biochem/physiol Actions: | γ-Aminobutyric acid (GABA) is a mammalian inhibitory neurotransmitter with multiple functions. It is crucial for the normal central nervous system (CNS) functioning. A few documented functions of GABA include its protective role in toxin-induced damage. It also elicits anti-hypertensive, anti-diabetic, anti-microbial, antioxidant, anti-allergy, anti-inflammatory, and anti-cancer effects. GABA might show beneficial effects on stress and sleep in humans. γ-Aminobutyric acid (GABA) is used to study the biological and biochemical processes mediated via the GABA receptors, GABAA and GABAB. |
| General description: | γ-Aminobutyric acid (GABA) is a non-protein amino acid associated with the brain. Being synthesized in the nervous system, it is packed into synaptic vesicles. It is present naturally in green tea, soybean, germinated rice, and in some fermented foods. |
| Packaging: | 10 mg in autosample vial |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 195 °C (dec.) (lit.) |
| UNSPSC | 12352106 |