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Abz-LFK(Dnp)-OH trifluoroacetate salt

SIGMA/A5855 - ≥97% (HPLC)

Synonym: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt

Empirical Formula (Hill Notation): C34H41N7O9 · xC2HF3O2
Molecular Weight: 691.73 (free base basis)
MDL Number: MFCD11045275
Linear Formula: C34H41N7O9 · xC2HF3O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A5855-1MG 1 mg
 $297.00
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assay ≥97% (HPLC)
color yellow
form film
InChI 1S/C34H41N7O9.C2HF3O2/c1-21(2)18-28(38-31(42)24-12-6-7-13-25(24)35)32(43)39-29(19-22-10-4-3-5-11-22)33(44)37-27(34(45)46)14-8-9-17-36-26-16-15-23(40(47)48)20-30(26)41(49)50;3-2(4,5)1(6)7/h3-7,10-13,15-16,20-21,27-29,36H,8-9,14,17-19,35H2,1-2H3,(H,37,44)(H,38,42)(H,39,43)(H,45,46);(H,6,7)/t27-,28-,29-;/m0./s1
InChI key BAXBDLHYKKDHEJ-BJRQXHFHSA-N
Quality Level 100 
SMILES string OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)c1ccccc1N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCNc3ccc(cc3[N+]([O-])=O)[N+]([O-])=O)C(O)=O
storage temp. 2-8°C
Amino Acid Sequence: Abz-Leu-Phe-Lys-DNP
Application: Abz-LFK(Dnp)-OH trifluoroacetate (TFA) salt is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. Abz-LFK(Dnp)-OH TFA has been used to study the development of new antibacterial calixarene derivatives, as well as the efficacy and toxicity of the antimicrobial peptide M33 as a possible antimicrobial agent in lung infections and sepsis.
Biochem/physiol Actions: Abz-LFK(Dnp)-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the C domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).
Features and Benefits: This compound is featured on the Angiotensin Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 1 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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