Amifostine trihydrate
SIGMA/A5922 - ≥97% (TLC), powder
Synonym: 2-
CAS Number: 112901-68-5
Empirical Formula (Hill Notation): C5H15N2O3PS · 3 H2O
Molecular Weight: 268.27
MDL Number: MFCD00453866
Linear Formula: C5H15N2O3PS · 3 H2O
Product Type: Chemical
assay | ≥97% (TLC) |
form | powder |
InChI | 1S/C5H15N2O3PS.3H2O/c6-2- |
InChI key | TXQPXJKRNHJWAX-UHFFFAOYSA |
Quality Level | 200 |
SMILES string | OP(SCCNCCCN)(O)=O.O.O.O |
storage temp. | 2-8°C |
Application: | Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible. |
Biochem/physiol Actions: | Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoeth |
Packaging: | 100 mg in poly bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264 - P270 - P301 + P312 + P330 - P501 |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥97% (TLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |