L-Ascorbic acid

SIGMA/A5960 - BioXtra, ≥99.0%, crystalline

Synonym: L-Threoascorbic acid; Antiscorbutic factor; Vitamin C

CAS Number: 50-81-7
Empirical Formula (Hill Notation): C₆H₈O₆
Molecular Weight: 176.12
EC Number: 200-066-2
MDL Number: MFCD00064328
Linear Formula: C₆H₈O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A5960-10MG	10 mg	$23.70 1/EA	Add To Favorites
45-A5960-25G	25 g	$53.20 1/EA	Add To Favorites
45-A5960-100G	100 g	$126.00 1/EA	Add To Favorites
45-A5960-500G	500 g	$431.00 1/EA	Add To Favorites

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This image depicts SKU: A5960-100G

Properties
Descriptions
Safety Info.
Basic Data

anion traces	sulfate (SO₄^2-): ≤0.05%
assay	≥99.0%
cation traces	Al: ≤0.0005%
	Ca: ≤0.0005%
	Cu: ≤0.0005%
	Fe: ≤0.0005%
	K: ≤0.005%
	Mg: ≤0.0005%
	Na: ≤0.005%
	NH₄⁺: ≤0.05%
	Pb: ≤0.001%
	Zn: ≤0.0005%
color	white to off-white
form	crystalline
ign. residue	≤0.1%
impurities	≤0.0005% Phosphorus (P)
	≤0.1% Insoluble matter
InChI	1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
mp	190-194 °C (dec.)
pH	1.0-2.5 (25 °C, 176 g/L in water)
product line	BioXtra
Quality Level	200
SMILES string	OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
solubility	H₂O: 0.5 M, clear, colorless
technique(s)	cell culture \| mammalian: suitable

Application:	• L-Ascorbic acid has been used to induce osteoblast differentiation from primary bone marrow cultures. • It has been used for the differentiation of hCMPCs (human cardiomyocyte progenitor cells) into cardiomyocytes. • It has been used to measure the mitochondrial electron transport chain (complex IV) activity.
Biochem/physiol Actions:	L-Ascorbic acid plays a role in production of neurotransmitters, carnitine and collagen synthesis. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species. Vitamin C exhibits anti-oxidant properties. Vitamin C is implicated in conferring protection against photoaging and anti-aging. Deficiency of vitamin C is associated with scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.
Caution:	May darken in storage.
General description:	Ascorbic acid is also referred to as Vitamin C. It contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Vitamin C is a water-soluble vitamin. Vitamin C is a part of citrus fruits, such as Indian gooseberry, broccoli, strawberries, brussels sprouts. L-ascorbic acid is the biologically active form of ascorbic acid. It is unstable and hydrophilic. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation.
Other Notes:	2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Packaging:	10 mg in glass bottle
Packaging:	25, 100, 500 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Purity	≥99.0%
mp	190-194 °C (dec.)
UNSPSC	12352209

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