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AM251

SIGMA/A6226 - >98% (HPLC), solid

Synonym: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide

CAS Number: 183232-66-8
Empirical Formula (Hill Notation): C22H21N4OCl2I
Molecular Weight: 555.24
MDL Number: MFCD01861181
Linear Formula: C22H21N4OCl2I
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A6226-10MG 10 mg
 $279.00
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45-A6226-50MG 50 mg
 $951.00
1/EA		 Add To Favorites

 

assay >98% (HPLC)
color white
form solid
InChI 1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
InChI key BUZAJRPLUGXRAB-UHFFFAOYSA-N
originator Sanofi Aventis
Quality Level 100 
SMILES string Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCCCC4
solubility DMSO: >10 mg/mL
  H2O: insoluble
Application: AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.
Biochem/physiol Actions: AM251 is a CB1 cannabinoid receptor antagonist.
Features and Benefits: This compound is featured on the Cannabinoid Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Other Notes: Salt content may vary.
Packaging: 10, 50 mg in glass bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
UNSPSC 12352200

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