Adenosine 5′-triphosphate disodium salt hydrate

SIGMA/A6419 - microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

Synonym: ATP disodium salt

CAS Number: 34369-07-8
Empirical Formula (Hill Notation): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
Molecular Weight: 551.14 (anhydrous basis)
MDL Number: MFCD00150755
Linear Formula: C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A6419-1G	1 g	$57.00 1/EA	Add To Favorites
45-A6419-5G	5 g	$181.00 1/EA	Add To Favorites
45-A6419-10G	10 g	$336.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A6419-10G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% (HPLC)
biological source	microbial
form	powder
InChI	1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key	NTBQNWBHIXNPRU-MSQVLRTGSA-L
product line	BioReagent
Quality Level	200
SMILES string	O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
solubility	H₂O: 50 mg/mL
storage temp.	−20°C
technique(s)	cell culture \| mammalian: suitable

Application:	Adenosine 5′-triphosphate disodium salt hydrate has been used: • as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites • in inflammasome activation assays in bone marrow derived macrophages • for the stimulation of macrophages • in nucleotide synthesis
Biochem/physiol Actions:	P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems
General description:	Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.
Packaging:	1, 5, 10 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352207

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