ABT-418 hydrochloride
SIGMA/A6476 - powder, ≥98% (HPLC)
Synonym: 3-
CAS Number: 147388-83-8
Empirical Formula (Hill Notation): C9H14N2O · HCl
Molecular Weight: 202.68
MDL Number: MFCD11045960
Linear Formula: C9H14N2O · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C9H14N2O.ClH/c1-7-6-9( |
| InChI key | VOXHERKWAIEJQF-QRPNPIFTSA |
| originator | Abbott |
| Quality Level | 100  |
| SMILES string | Cl.CN1CCC[C@H]1c2cc(C)no2 |
| solubility | H2O: soluble 15 mg/mL |
| storage condition | desiccated |
| Application: | ABT-418 hydrochloride has been used as a nicotinic acetylcholine receptor (nAChR) agonist to test its effect on spatial memory improvement in attention deficit hyperactivity disorder (ADHD) rat model |
| Application: | ABT-418 [(S)-3-methyl-5-(1 methyl-2-pyrrolidinyl)iso |
| Biochem/physiol Actions: | Neuronal nicotinic acetylcholine receptor agonist with cognition enhancing and anxiolytic activities. |
| Features and Benefits: | This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | ABT-418 is an α4β2 agonist of nicotinic receptors. |
| Legal Information: | Subject to U.S. Patent No. 5409946 and sold under license from Abbott Laboratories. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H300 + H310 + H330 |
| Precautionary statements | P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 7/9-22-28-36/37-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352200 |