Albumin human
SIGMA/A6608 - recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)
Synonym: rHSA
CAS Number: 70024-90-7
Empirical Formula (Hill Notation): C2936H4624N786O889S41
Molecular Weight: 66471.53
MDL Number: MFCD00081418
Linear Formula: C2936H4624N786O889S41
Product Type: Chemical
Human serum albumin is a 66 kDa predominantly monomeric protein with one free sulfhydryl group and 17 intrachain disulfide bonds.
| assay | ≥99% (agarose gel electrophoresis) |
| biological source | human |
| concentration | 10% in aqueous buffer |
| form | aqueous solution |
| InChI | 1S/C3F8/c4-1(5,2(6,7)8)3( |
| InChI key | QYSGYZVSCZSLHT-UHFFFAOYSA |
| mol wt | monomer ~67 kDa |
| Quality Level | 200  |
| recombinant | expressed in Saccharomyces cerevisiae |
| storage temp. | 2-8°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P02768  |
| Analysis Note: | Endotoxin tested |
| Application: | Albumin human has been used: • to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements • to study its proteolytic activities under reducing conditions • in the medium for stem cell cultivation |
| Application: | This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells. |
| Biochem/physiol Actions: | Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices. |
| Biochem/physiol Actions: | Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood. |
| General description: | Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group. |
| Other Notes: | View more information on human serum albumin . |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (agarose gel electrophoresis) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |