(±)-AMPA
SIGMA/A6816 - solid
Synonym: (±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrate
Empirical Formula (Hill Notation): C7H10N2O4
Molecular Weight: 186.17
MDL Number: MFCD00213388
Linear Formula: C7H10N2O4
Product Type: Chemical
| color | white |
| form | solid |
| InChI | 1S/C7H10N2O4.H2O/c1-3-4(6 |
| InChI key | HFISYNCCKQHIAM-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | O.Cc1onc(O)c1CC(N)C(O)=O |
| solubility | 0.1 M HCl: 3.5 mg/mL |
| 0.1 M NaOH: 4.3 mg/mL | |
| 1 M HCl: 50 mg/mL | |
| DMSO: 4.3 mg/mL | |
| H2O: 1 mg/mL (warm) |
| Application: | (±)-AMPA has been used: • in vivo • whole-cell patch-clamp recording in Müller glial cells • to test its excitotoxic effects in hippocampal slice cultures • in retinal horizontal cells (HCs) culture to test its effect on Ca2+ signals |
| Biochem/physiol Actions: | Potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors. |
| Packaging: | 1, 5, 10 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352100 |

