Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate

SIGMA/A6885 - ≥98.0% (HPLC), powder

Synonym: 3′,5′-Cyclic AMP sodium salt; cAMP-Na

CAS Number: 37839-81-9
Empirical Formula (Hill Notation): C₁₀H₁₁N₅NaO₆P · H₂O
Molecular Weight: 369.20
MDL Number: MFCD00069736
Linear Formula: C₁₀H₁₁N₅NaO₆P · H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A6885-25MG	25 mg	$40.70 1/EA	Add To Favorites
45-A6885-100MG	100 mg	$86.80 1/EA	Add To Favorites
45-A6885-500MG	500 mg	$276.00 1/EA	Add To Favorites
45-A6885-1G	1 g	$413.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A6885-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98.0% (HPLC)
color	white
form	powder
InChI	1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
InChI key	BXJBFCKTIWRKMQ-MCDZGGTQSA-M
Quality Level	200
SMILES string	[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O
solubility	H₂O: 10 mg/mL
storage temp.	−20°C

Application:	Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.
Biochem/physiol Actions:	Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA).
Biochem/physiol Actions:	Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
Features and Benefits:	This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the Phosphodiesterases and PKA & PKG pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	1 g in poly bottle
Packaging:	25, 100, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (HPLC)
Storage Temp.	−20°C
UNSPSC	41106305

To Order From a Quote